Brown University Health Laboratories

Common Tests

Please note, this guide has been provided as a simple reference. For further clarification or for help understanding laboratory results, please contact your health care provider.

Blood Profile Tests

Alkaline Phosphatase

Alkaline phosphatase is an enzyme found primarily in the liver and bones. These levels are usually higher in pregnant women and children due to its role in the bone-making process. Elevated levels may be an indication of bone, kidney or liver disorders.

Albumin

Albumin is one part of a group of serum proteins and a component of total serum protein. Low values may be a result of hepatic (liver) or renal (kidney) disorders. Higher values may indicate dehydration.

ALT

Alanine aminotransferase (ALT) is an enzyme involved in the metabolism of the amino acid alanine. ALT is found in a number of tissues but in higher concentration in the liver. Elevated levels can be due to certain medications or extensive exercise, but can also be a sign of liver disorders.

AST

Aspartate aminotransferase (AST) is an enzyme found in high concentration in the heart muscle, liver cells, skeletal muscle cells and to a lesser degree in other tissues. Elevated levels of AST can indicate muscle trauma, heart damage or damage to the liver.

BUN

Blood urea nitrogen (BUN) is an end product of protein metabolism, which is cleared by the kidneys. Elevated levels may be an indication of kidney disorders or diuretics.

CEA

Carcinoembryonic antigen (CEA) is a glycoprotein found in a variety of human tissues which circulates at low levels in the blood, up to 3.ng/ml for non-smokers and 5.0 ng/ml for smokers. Elevations in CEA may be due to inflammation, benign tumors or malignant tumors.

Cholesterol

Cholesterol is a normal body constituent, used in the structure of cell membranes, synthesis of bile acids and steroid hormones. It is one of the major lipids in the body. Excess cholesterol in the blood has been correlated with cardiovascular disease.

Creatinine

Creatinine is a by-product of muscle tissue metabolism. Elevations might suggest kidney or vascular disease. High protein diets may cause mild elevations.

Fructosamine or Glycosylated Serum Protein

Fructosamine and glycosylated serum protein are both time-averaged indicators of blood glucose levels over the previous two or three weeks. They are used to assess the glycemic status of diabetics.

Globulin

Globulin is a component of total serum protein. Abnormal levels have been found in individuals with immune disorders, infections and other diseases.

Glucose

This test measures blood sugar levels. This test is very sensitive to food intake and requires a period of fasting in order to reflect an accurate representation of blood sugar levels.

GGT

Gama glutamyl transpeptidase (GGT) is an enzyme found in the liver, bile ducts and kidneys. Higher than normal levels may indicate hepatitis, heavy alcohol use or the use of certain medications.

HDL Cholesterol

High density lipoproteins (HDL) in high levels have shown to provide a protective effect against coronary heart disease. It is sometimes referred to as the "good cholesterol."

LDL Cholesterol

Low density lipoproteins (LDL) in elevated levels can be related to coronary heart disease. It is sometimes referred to as the "bad cholesterol."

NT-proBNP

NT-proBNP is a synthesized prohormone used as a cardiovascular marker. Elevations may be caused by cardiac diseases, certain pulmonary diseases, hyperthyroidism, diabetes, liver cirrhosis and/or renal failure.

PSA

Prostate Specific Antigen (PSA) can indicate the condition of the prostate gland in men. Elevations may indicate a risk for prostate cancer; however other benign factors have also been known to elevate PSA values.

Total Bilirubin

This by-product of the breakdown of red blood cells is made into a water-soluble form in the liver. Elevations can indicate chronic liver disease, gall bladder disease or anemia.

Total Protein

High values may be an indicator of dehydration or chronic inflammation. Extremely low values may be associated with malnutrition or peripheral edema.

Triglycerides

Triglycerides comprise the largest portion of fat in the blood. In higher elevations it can be an indication of diabetes, acute alcoholism, liver disease or renal failure. Triglycerides may also be elevated in non-fasting samples.

Urinalysis

Glucose

Glucose, not normally found in the urine, can suggest diabetes or other illnesses.

pH

Elevated values may indicate an infection or metabolic disease. Low values may indicate dehydration or diabetes. It may also indicate specimen adulteration.

Leukocyte Esterase

Leukocyte esterase is an enzyme found in white blood cells. When present it can be an indication of kidney or urinary tract infections.

Cotinine

Cotinine is a metabolite of nicotine and an indicator of tobacco or nicotine use. It will be present in the urine from all forms of tobacco including cigarettes, cigars, chewing tobacco and other smokeless tobacco products.

Protein

Elevated protein levels can be an indicator of kidney disease.

Creatinine

Creatinine is used to evaluate kidney function

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